Evaluation of Antibacterial Activity of Tetmosol® against some Clinical Isolates

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Published: Aug 23, 2020
Keywords:
Evaluation of antibacterial, Activity, Tetmosol®,, Disinfectant, Clinical isolates

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Clement O. Anie
Johnson D. Jemikalajah
Merit O. Meshack
Oghenejobo Michael

Abstract

The study was carried out to evaluate the antibacterial activities of Tetmosol® using some clinical bacterial isolates. The broth dilution and agar well diffusion methods were used to determine the minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC). The result indicated that the sample of tetmosol was effective as a disinfectant with broad spectrum of activity. The MIC of Tetmosol using broth technique was 1.2125 %v/v, 0.60625 %v/v, O.60625 %v/v, 0.60625 %v/v for Staphylococcus aureus, Streptococcus pyogene, Escherichia coli, Pseudomonas aeruginosa respectively. The MBC using agar technique was 6% and that of broth technique 9%. Susceptibility testing of the microorganism to Tetmosol, showed the highest zones of inhibition were 11 mm,14 mm, 12 mm, 10 mm for Staphylococcus aureus, Streptococcus pyogene, Escherichia coli, Pseudomonas aeruginosa respectively. The phenol coefficient of Tetmosol was found to be 9.1 which indicated that Tetmosol was more potent than phenol. The use of Tetmosol® in hospital, water bath and clinics in Nigeria is recommended.

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How to Cite
Anie, C. O. ., Jemikalajah, J. D. ., Meshack, M. O. ., & Michael, O. (2020). Evaluation of Antibacterial Activity of Tetmosol® against some Clinical Isolates. Nigerian Journal of Pharmaceutical and Applied Science Research, 9(1), 63–68. Retrieved from https://nijophasr.net/index.php/nijophasr/article/view/335
Issue
Vol. 9 No. 1 (2020)
Section
Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Author Biographies

Clement O. Anie

Department Of Pharmaceutical Microbiology, Faculty Of Pharmacy, Delta State University, Abraka, Delta State, Nigeria

Johnson D. Jemikalajah

Department of Microbiology, Faculty of Science Delta State University Abraka, Delta State, Nigeria.

Merit O. Meshack

Department Of Pharmaceutical Microbiology, Faculty Of Pharmacy, Delta State University, Abraka, Delta State, Nigeria

Oghenejobo Michael

Department Of Pharmaceutical Microbiology, Faculty Of Pharmacy, Delta State University, Abraka, Delta State, Nigeria

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