Antibacterial Potential of Ginger (Zingiber officinale) Extract against Bacterial Isolates of Pulmonary Infections
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Abstract
There has been a lot of interest in the investigation of natural materials as sources of new antibacterial agents. Therefore, this study aims at the determination of antibacterial potential of ginger extracts against bacteria isolates of pulmonary infections. The ginger rhizome, used in the study was obtained at the botanical garden of the Department of Pharmacognosy Delta State University Abraka where extraction processes were also carried out using methanol, and sterile distilled water. Standard bacteriological culture method was used for isolation of bacteria from the pulmonary infections. Three isolates of Streptococcus pneumonia (5.66%), six strains of Klebsiella pneumonia (11.32%), sixteen strains of Staphylococcus aureus (30.18%), ten isolates of Escherichia coli (18.86%), ten strains of Pseudomonas aeruginosa (18.86%) and eight isolates of Proteus mirabilis (15.09%) were tested against extracts of ginger using agar diffusion plate method. The result revealed a significant effect of methanol extracts of the ginger in all the isolates tested, but there were some resistant strains observed in the conventional antibiotics; while the sensitivity pattern of crude extract of ginger were less effective compared to methanol extract. The present work indicates that natural rhizome (ginger) has considerable antibacterial activities against bacterial isolates of pulmonary infections.
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