Powdered Oil Palm (Elaesis guineensis Jacq) Leaf as Remedy for Hydrocarbon induced Liver Damage in Rats
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Humans are faced with a number of diseases and chemical toxicity due to sustained pollution of environment. One of the management strategies adopted in recent times is the use of herbs. This is the driving force for this study. Ninety six female rats were mobilized for this study and were divided into six groups of sixteen rats each. Rats in group A served as control and were fed with diet devoid of any treatment while rats in groups B and C were fed with diets treated with varying amounts of ground Elaesis guineensis leaf. Rats in group D were fed with hydrocarbon adulterated diet. Rats in groups E and F were fed with adulterated diet mixed with the same amounts of ground Elaesis guineensis leaf as in groups B and C. Oxidative stress indicators and histological analysis were carried out on the rat’s liver after exposure period of three and six months respectively. The results show that pretreatment of hydrocarbon adulterated diet with Elaesis guineensis leaf normalized values of lipid peroxidation (LP), superoxide dismutase activity (SOD), catalase activity (CAT) and xanthine oxidase activity (XO) relative to control values. Histological analyses indicate protective influence of Elaesis guineensis leaf against harmful consequence of hydrocarbon on the liver. It is apparent that the leaves of Elaesis guineensis could be used in the management of hydrocarbon linked liver damage.
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Références
Abdul-Razak M (2009), The effects of Oil Palm Fronds (Elaeis Guineensis) extract on Lipid Profile and Antioxidant Enzyme Activity in Sprague Dawley Rats, MSc Thesis, Universiti Putra Malaysia.
Achuba F.I. and P.E. Awhin (2009), Protective influence of antioxidant vitamins on hematological indices of rabbits fed crude-oil-contaminated diet. Toxicol Environ Chem 9(3):505 — 510
Achuba, F.I. (2015) .Effect of petroleum products treatment of soil on succinate dehydogenase and lactate dehydogenase activities in cowpea (Vigna unguiculata) and Maize (Zea mays) seedlings. Am J Exp Agric 5(5): 498-508
Achuba, F.I. (2018a). Protective influence of Elaesis guineensis leaf in diet on petroleum-mediated kidney damage in rat. Nig J Pharm Appl Sci Res 7(2): 33-38
Achuba, F.I (2018b). Evaluation of the protective effects of bitter leaf (Vernonia amygdalina) on haematological indices of rats fed with crude oil treated diet. J Appl Sci Environ Mgt 22 (4) 489 – 492.
Achuba, F.I. (2008). African land snail Achatina marginatus, as bioindicator of environmental pollution. North- Western J Zool 4 (1): 1-5
Achuba, F.I. (2010). Spent engine oil mediated oxidative stress in cowpea (Vigna unguiculata) seedlings. EJEAFChe. 9(5): 910-917
Achuba, F.I. and Otuya, E.O. (2006). Protective influence of vitamins against petroleum induced free radical toxicity in rabbit. Environmentalists 26 (4): 295–300.
Achuba, F.I. and Nwokogba, C.C. (2015). Effects of honey supplementation on hydrocarbon-induced kidney and liver damage in Wistar albino rats. Biokemistri 27 (1): 50–55.
Achuba, F.I. and Ogwumu, M. D. (2014a). Possible protective role of palm oil and beef liver on the kidney and liver of wistar albino rats fed diesel-contaminated diet. Biokemistri 26 (4) 124–129.
Achuba, F.I. and Ogwumu, M.D. (2014b). Effect of palm oil and beef liver on diesel-induced haematotoxicity in wistar albino rats. Biokemistri 26 (4) 120–123
Achuba, F.I. and Osakwe, S. A. (2003) Petroleum induced free radical toxicity in Africa catfish (Clarias gariepinus) Fish Physiol. Biochem. 29(2):97-103
Achuba, F.I, Ubogu, L.A. and Ekute, B.O. (2016). Moringa oleifera attenuates crude oil contaminated diet induced biochemical effects in wistar albino rats. UK J Pharma. Biosci. 4(5):70-77
Al-Attar, A.M , Alrobai, A.A. and Almalki, D.A. (2017)Protective effect of olive and juniper leaves extracts on nephrotoxicity induced by thioacet.amide in male mice Saudi J Biol Sci ;24(1) 15-22
Almeda, R, Wambaugh, Z, Wang Z., Hyatt, C., Liu Z, and Buskey, E. J. (2013a) Interactions between zooplankton and crude oil: Toxic effects and bioaccumulation of polycyclic aromatic hydrocarbons. PLoS ONE 8(6): e67212. https://doi.org/10.1371/journal.pone.0067212.
Almeda, R, Wambaugh, Z, Chai, C, Wang, Z., Liu, Z. and Buskey E. J. (2013b). Effects of crude oil exposure on bioaccumulation of polycyclic aromatic hydrocarbons and survival of adult and larval stages of gelatinous zooplankton. PLoS ONE 8(10): e74476. https://doi.org/10.1371/journal.pone.0074476
Anyanji, V.U, Hair, B.B. and Mohamed S. (2013). Acute toxicity assessment of oil palm (Elaeis guineensis) leaf extract in rats. J Med Plant Res 7: 1022-1029.
Azeez, O.M., Akhigbe, R.E., and Anigbogu, C.N. (2013). Oxidative status in rat kidney exposed to petroleum hydrocarbons. J Nat Sci Biol Med 4(1), 149–154. http://doi.org/10.4103/0976-9668.107280
Bergmeyer, H.V., Gacoehm, K. and Grass, M. (1974). In: Met.hods of Enzymatic Analysis, Bergmeyer, H. V (eds).New York: Academic Press. 2: 428–429.
Chong, K.H, Zuraini, Z, Sasidharan, S, Devi, P.V.K., Latha, L.Y and Ramanathan, S. (2008). Antimicrobial activity of Elaeis guineensis leaf. Pharm online. 3:379-386
Ezedom, T. and Asagba, S.O. (2016). Effect of a controlled food-chain mediated exposure to cadmium and arsenic on oxidative enzymes in the tissues of rat. Toxicol Reports 3:708–715
Gutteridge, J.M.C. and Wilkins, S. (1982) Copper-dependent hydroxyl radical damage to ascorbic acid. FEBS Letters (137): 327.329.
Ibraheem, Z.O., Sattar, M.A., Abdullah, N.A., Hassan, R. and Johns, E.J. ( 2012).Toxicity, phytochemical content and antioxidant activity assessment studies for standardized ethanolic fraction of palm oil leaf extract. Pharm. Comm. 2(1): 21-30.
Ita, S.O, Akpanyung, E.O., Robert, A.S., Aluko, E.O., Eseabasi, F.O and Sunday-Essien M.U. (2016). Evaluation of some inflammatory biomarkers in male albino wistar rats following ingestion of crude oil and the role of bee honey, vitamins C and E. Modern Res Inflammation 5: 55-62. http://dx.doi.org/10.4236/mri.2016.53006
Jaffri, J.M., Mohamed, S., Ahmad, I. N., Mustapha, N.M., Manap, Y.A. and Rohimi, N. (2011). Effects of catechin-rich Elaesis guineensis leaf extract on normal and hypertensive rats kidney and liver. Food Chem. 128:433–441
Misra, H.P. and Fridovich,I. (1972). The role of superoxide anion in the autooxidation of epinephrine and a sample assay for superoxide dismutase. J. Biol. Chem. 247: 3170-3175
Mohamed, S. (2014). Oil palm leaf: A new functional food ingredient for health and disease prevention. J Food Process Technol 5: 300. doi:10.4172/2157-7110.1000300
Mohamed S, Lee Ming, T. and Jaffri, J.M. (2013) Cognitive enhancement and neuroprotection by catechin-rich oil palm leaf extract supplement. J Sci Food Agric 93: 819-827.
Nwaogu, L.A. and Onyeze, G.O.C. (2014). Effect of chronic exposure to petroleum hydrocarbon pollution on oxidative stress parameters and histology of liver tissues of native fowl (Gallus domestics). Int J Biochem Res Rev 4(3)233-242
Obahiagbon, F.I. (2012). A Review: Aspects of the African oil palm (Elaeis guineesis jacq.) and the implications of its bioactives in human health. Am J Biochem Mol Biol 2:106-119.
Okpoghono, J., Achuba, F.I. and George, B.O. (2018a). Protective effect of Monodora myristica extracts on crude petroleum oil contaminated catfish (Clarias gariepinus) diet in rats. Int J Vet Sci Med https ://doi.org/10.1016/j.ijvsm.2018.03.006
Okpoghono, J, George, B.O. and Achuba, F.I. (2018b). Assessment of antioxidant indices after incorporating crude oil contaminated catfish and African nutmeg (Monodora Myrstica) extracts into rat diet. J Appl Sci Environ Manage 22 (2) 197 – 202.
Rajavel, V., Abdul Sattar, M. Z., Abdulla, M.A., Kassim, N. M. and Abdullah, N. A. (2012). Chronic administration of oil palm (Elaeis guineensis) leaves extract attenuates hyperglycaemic-induced oxidative stress and improves renal histopathology and function in experimental diabetes. Evidence-Based Complementary and Alternative Medicine. Article ID: 195367 doi:10.1155/2012/1953671
Rajoo, A., Sasidharan, S., Jothy, S. L., Ramanathan, S. and Mansor, S. M. (2013). Ultrastructural study of Elaeis guineensis (oil palm) leaf and antimicrobial activity of its methanol extract against staphylococcus aureus. Trop J Pharmaceut Res. 12:419-423.
Rani, P.,Meena, U. K. and Karthikeyan, J. (2004). Evaluation of antioxidant properties of berries. Indian J Clin Biochem 19: 103-110.
Rikans, L.E., Moore, D.R. and Snowden, C. D. (1991). Sex-dependent differences in the effects of aging on antioxidant defense mechanisms of rat liver. Biochimica et Biophysica Acta (BBA) - General Subjects 1074(1): 195-200. https://doi.org/10.1016/0304-4165(91)90061-K
Rosalina, T.R.T., Mohamed S., Samaneh, G. F., Noordin, M. M., Goh, Y. M.and Manap, M. Y. A. (2011). Polyphenol rich oil palm leaves extract reduce hyperglycaemia and lipid oxidation in STZ-rats. Int Food Res J 18:179-188.
Rout, S.P, Choudary, K.A., Kar, D. M., Das, L. and Jain, A. (2009). Plants in traditional medicinal system-future source of new drugs. Int J Pharm Pharm Sci 5(4):137-140
Sasidharan, S., Logeswaran, S. and Latha, L.Y. (2012)Wound healing of Elaeis guineensis leaf extract ointment. Int J Mol Sci 13(1): 336-347.
Settle, T. and Klandorf, H. (2014) The Role of uric acid as an antioxidant in neurodegenerative disease pathogenesis. Brain Disord Ther 3:129. doi:10.4172/2168-975X.1000129
Uboh, F.E., Akpanabiatu, M. I., Ndem, J. I., Alozie, Y. and Ebong P.E. ( 2009). Comparative nephrotoxic effect associated with exposure to diesel and gasoline vapours in rats. J Toxicol Environ Health Sci.1:68–74.
Uboh, F.E., Ufot, S.U. and Eyong, E. U. (2013) Comparative effect of withdrawal from exposure on gasoline and diesel induced nephrotoxicity in male albino Wistar rats. J Clin Toxicol. 3:170. doi: 10.4172/2161-0495.1000170
Vijayarathna, S. and Sasidharan, S.( 2012). Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines. Asian Pac. J. Trop. Biomed. 2(10): 826-829.
Yin, N.S., Abdullah, S. and Phin, C.K. (2013) Phytochemical constituents from leaves of Elaeis guineensis and their antioxidant and antimicrobial activities. Int J Pharm Pharmaceut Sci 5: 137-14