The Effect of Jatropha tanjorensis on Blood Electrolyte Concentrations of Albino Wistar Rats
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Abstract
The aim of this research work is to determine the effect of Jatropha tanjorensis on blood electrolyte concentration. Forty rats were used for this work, the rats were divided into two groups; the control and the treated group, and each group consists of twenty rats with ten males and ten females. 0.5 g/kg body weight of the extract of Jatropha tanjorensis was administered to the rats in the extract group for a period of twenty eight (28) days. The rats were sacrificed after 28 days and blood samples were collected into a clean lithium heparinised tube and the blood sample were analyzed for sodium, Potassium, chloride, bicarbonate, creatinine and urea concentrations. There were statistically significant increases (p< 0.001) in the mean concentrations of sodium, potassium and Chloride in both the male and female wistar rats. There were no significant differences in the creatinine, urea and bicarbonate of both the male and female rats when compared with control group. Therefore Jatropha tanjorensis causes significant increases in sodium, potassium and chloride concentration in the blood.
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